Genetics 101 Blog

PCOS – The Leading Cause of Female Infertility! Polycystic ovary syndrome, or PCOS in short, is a common condition in women which prevents 12-21% of them from getting pregnant. However, thanks to recent advances in reproductive medicine, getting pregnant with PCOS has become possible. Insulin resistance is the hallmark of PCOS. Excessive blood insulin adversely…

What is multiple miscarriage and why do you need to know about it? A “miscarriage” is the involuntary termination of pregnancy. Roughly one of eight pregnancies ends with a miscarriage. Most cases occur during the first trimester and it is the most common complication of early pregnancy. Miscarriages were referred to as “recurrent” when it…

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Causes of Multiple Miscarriage: Multiple miscarriages, which was classically defined as >3 consecutive pregnancy losses has recently been redefined as >2 pregnancy loss, owing to an increase in the prevalence of childless couples. Years of research in the field have identified anti-phospholipid antibody (aPL) syndrome (APS), uterine/endocrine/chromosomal abnormalities as the leading causes of multiple miscarriage….

Endometriosis and Infertility: Affects 5-10% of women of reproductive age, Of every 10 women with endometriosis, 2 to 5 also suffer from infertility. It is a disease in which the lining of the uterus (or endometrium) grows in other parts of the body, causing excessive pain during menstrual cycle. The primary symptom is usually pelvic…

What is multiple miscarriage? The term “miscarriage” means involuntary pregnancy loss. It occurs in 15% of apparently normal couples, and become “recurrent” in 2% to 3%. Traditionally, miscarriage events are recurrent when it involves loss of 3 or more consecutive pregnancies, usually before 20 weeks of gestation, with or without previous live births. Currently accepted…

Is cancer inherited? Should I be worried if my family has a history of cancer? These are questions that may have crossed your mind when loved family members suffered the torment of cancer. It is well-acknowledged that environmental factors such as smoking, diet, and infections contribute significantly to the risk of developing cancer. Nonetheless, the…

Thanks to public education campaigns, smoking is on the decline. However, many smokers find it hard to kick the habit. Smoking is highly addictive because nicotine penetrates into the brain where it binds to nicotine receptors on neurons, which are then stimulated to produce the neurotransmitter, dopamine. Dopamine is responsible for many effects and is…

In this age of healthy living, much emphasis has been placed on advocating an active lifestyle, nutritionally balanced diet, and adequate daily exercise to mitigate the risk of developing health complications. One of the major illnesses that everyone hopes to avoid is heart disease. The human heart is a muscle that pumps blood in our…

Mutations in Genes Small harmless variations in genes lead to the production of proteins which are slightly different, causing subtle but observable disparity (or “traits”) between individuals such as eye color or skin tone. However, when the variation is deleterious and results in a protein that affects normal function and physiology, the consequence is sickness…

Despite recent claims by Illumina, the $1000 genome is still a myth – companies benchmark the bare bone cost of sequencing, not including the cost of sample collection, shipping, DNA purification and most importantly, the cost of genome data analysis, annotation and reporting which eclipses the cost of sequencing the genome. In post sequencing analysis…

Genetic testing has been in the news recently, and with improvements in technology has become much cheaper and more accessible for consumers. So you may be wondering, is genetic testing for me? For my family? And should I be asking my doctor for one? However as with any new technology, there remains a lot of…

I have little self-control when it comes to Big Mac, McNuggets, and french fries at McDonald’s restaurant. Its mesmerizing taste and smell make me forget all about the excess calories I am about to ingest until I step on a scale, which serves as a stern reminder of the awful reality in weight management. Like…

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