Jeff’s Story

Taking large amounts of pain medications was wearing on Jeff, but it was the only way he could manage, until he took a Pillcheck™ test.


Jeff sustained significant injuries to his right foot following a motorcycle accident and needed to take high doses of different pain medications to manage the excruciating pain. At the hospital, Jeff was treated with Morphine following orthopedic surgery. Upon discharge, he was given Tylenol 3, but did not get pain relief.  His doctor eventually prescribed high doses of Oxycontin, which managed to control the pain somewhat, but was not very effective at providing long term pain relief.  Jeff was beginning to get concerned about becoming addicted to these potent painkillers — until he took a Pillcheck™ test.

How Pillcheck Helped

The test results revealed that Jeff does not effectively convert both codeine (a component of Tylenol 3) and Oxycontin to morphine due to mutations in the CYP2D6 gene. This finding explained why Oxycontin did not provide adequate pain relief even at such high doses. For patients like Jeff, Morphine is more effective at managing pain. With this new information, Jeff’s doctors developed an alternative treatment plan that included Gabapentin (to treat nerve pain) and a sustained-release formulation of Morphine, along with physiotherapy sessions.  Jeff’s foot healed and his pain was managed properly; he felt much better and was able to return to work.

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